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Supervised versus unsupervised primaquine radical cure for the treatment of falciparum and vivax malaria in Papua, Indonesia: a cluster-randomised, controlled, open-label superiority trial

Abstract:
Background
There is a high risk of Plasmodium vivax recurrence in patients treated for Plasmodium falciparum malaria in co-endemic areas. Primaquine radical cure has the potential to reduce P vivax recurrences in patients presenting with P falciparum as well as P vivax malaria but is undermined by poor adherence to the currently recommended 14-day regimen. We aimed to assess the efficacy and safety of supervised versus unsupervised primaq... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/s1473-3099(21)00358-3

Authors


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Funder identifier:
https://ror.org/011kf5r70
Grant:
1134989
1104975
Funding agency for:
Simpson, JA
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Funding agency for:
Price, RN
Grant:
200909
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Funder identifier:
https://ror.org/0456r8d26
Grant:
INV-007122
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Funder identifier:
https://ror.org/023wsvq95
Grant:
72904


Publisher:
Elsevier
Journal:
Lancet Infectious Diseases More from this journal
Volume:
22
Issue:
3
Pages:
367-376
Publication date:
2021-10-25
DOI:
EISSN:
1474-4457
ISSN:
1473-3099


Language:
English
Pubs id:
1206090
Local pid:
pubs:1206090
Deposit date:
2021-10-30
ARK identifier:

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