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Identification and characterization of three members of the human SR family of pre-mRNA splicing factors.

Abstract:

SR proteins have a characteristic C-terminal Ser/Arg-rich repeat (RS domain) of variable length and constitute a family of highly conserved nuclear phosphoproteins that can function as both essential and alternative pre-mRNA splicing factors. We have cloned a cDNA encoding a novel human SR protein designated SRp30c, which has an unusually short RS domain. We also cloned cDNAs encoding the human homologues of Drosophila SRp55/B52 and rat SRp40/HRS. Recombinant proteins expressed from these cDN...

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Publication status:
Published

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Journal:
The EMBO journal
Volume:
14
Issue:
17
Pages:
4336-4349
Publication date:
1995-09-05
EISSN:
1460-2075
ISSN:
0261-4189
URN:
uuid:64cb87d9-ad80-4583-9cb7-0ef081b12894
Source identifiers:
102716
Local pid:
pubs:102716

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