Diagnosis and treatment of postpartum haemorrhage: a race against time

Journal article : Review

Postpartum haemorrhage (PPH) is common, affecting an estimated 13% of women having vaginal birth and 31% of women having caesarean birth. Successful management of PPH requires early and accurate diagnosis and effective treatment. A systematic review found that subjective visual estimation of blood loss misses 52% of PPH diagnoses at vaginal birth (pooled sensitivity 48%, 95% CI 44-53), and probably more at caesarean birth. The WHO-International Federation of Gynecology and Obstetrics-International Confederation of Midwives consolidated guidelines on PPH therefore recommend objective quantification of blood loss with products such as a calibrated blood collection drape. When supported by a robust implementation strategy and a first-response treatment bundle, objective measurement of blood loss and monitoring of vital signs has been shown to diagnose PPH accurately and early, and improve clinical outcomes. Refractory PPH can progress to life-threatening PPH, which should be managed by a multidisciplinary team providing aggressive resuscitation and targeted treatment. Saving the life of a woman with excessive postpartum bleeding is a race against time. The six delays to avoid are: (1) in the diagnosis (by use of objective cumulative blood loss measurement and early trigger criteria), (2) in the first-response treatment (by authorising midwives to administer all components of a standardised bundle of interventions), (3) in the escalation (by use of explicit escalation criteria and red flags), (4) in the use of temporising measures (eg, non-pneumatic anti-shock garment), (5) in the identification and targeted management of any specific causes of bleeding, and (6) in the provision of blood and blood products. Quick actions to avoid these delays can mean the difference between life and death for a woman with PPH.

Authors: Coomarasamy, A; Devall, AJ; Bell, S; Sindhu, KN; Mammoliti, K-M

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Elsevier
• Journal: Lancet More from this journal
• Volume: 408
• Issue: 10549
• Pages: 83-92
• Place of publication: England
• Publication date: 2026-06-12
• Acceptance date: 2026-05-20
• DOI: 10.1016/s0140-6736(26)01031-7
• EISSN: 1474-547X
• ISSN: 0140-6736
• Pmid: 42285120
• Language: English
• Keywords: maternal morbidity and mortality; health disparities and racial or ethnic minority health research; minority health; postpartum hemorrhage; pregnancy; contraception/reproduction; reproductive health and childbirth; maternal health; women's health
• Subtype: Review