Journal article
Studies of mefloquine bioavailability and kinetics using a stable isotope technique: a comparison of Thai patients with falciparum malaria and healthy Caucasian volunteers.
- Abstract:
-
1 A mefloquine hydrochloride tablet (250 mg base equivalent to 4.8 +/- 0.6 mg kg-1; mean +/- s.d.) and deuterium labelled mefloquine hydrochloride solution (250 mg base) were given to six adult male Thai patients with acute falciparum malaria and six healthy Swiss adult male volunteers (equivalent to 3.5 +/- 0.1 mg kg-1). 2 The relative bioavailability of the tablet formulation derived from comparison of the areas under the plasma concentration-time curves was similar in both groups; 87 +/- 1...
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- Publication status:
- Published
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- Publisher copy:
- 10.1111/j.1365-2125.1987.tb03133.x
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Authors
Bibliographic Details
- Journal:
- British journal of clinical pharmacology
- Volume:
- 24
- Issue:
- 1
- Pages:
- 37-42
- Publication date:
- 1987-07-01
- DOI:
- EISSN:
-
1365-2125
- ISSN:
-
0306-5251
- Source identifiers:
-
42870
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:42870
- UUID:
-
uuid:6432ef69-22d4-4220-bffa-0fbefc474208
- Local pid:
- pubs:42870
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 1987
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