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Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study

Abstract:

Background

Dementia with Lewy Bodies (DLB) is the second most common form of dementia in the elderly but has been overshadowed in the research field, in part due to similarities between DLB, Parkinson's (PD) and Alzheimer’s diseases (AD). So far, no large-scale genetic study of DLB has been performed. To better understand the genetic basis of DLB, we have performed a genome-wide association study, with the aim of identifying genetic risk factors for this disorder

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1016/s1474-4422(17)30400-3

Authors


Guerreiro, R More by this author
Kun-Rodrigues, C More by this author
Hernandez, DG More by this author
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Wellcome Trust More from this funder
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Publisher:
Elsevier Publisher's website
Journal:
Lancet Neurology Journal website
Volume:
17
Issue:
1
Pages:
64-74
Publication date:
2017-12-16
Acceptance date:
2017-11-03
DOI:
EISSN:
1474-4465
ISSN:
1474-4422
Pubs id:
pubs:813077
URN:
uri:64125b0e-cad4-4418-892a-fef17f4af038
UUID:
uuid:64125b0e-cad4-4418-892a-fef17f4af038
Local pid:
pubs:813077

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