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Effect of intra-membrane C 60 fullerenes on the modulus of elasticity and the mechanical resistance of gel and fluid lipid bilayers

Abstract:

Penetration and partition of C60 to the lipid bilayer core are both relevant to C60 toxicity, and useful to realise C60 biomedical potential. A key aspect is the effect of C60 on bilayer mechanical properties. Here, we present an experimental study on the mechanical effect of the incorporation of C60 into the hydrophobic core of fluid and gel phase zwitterionic phosphatidylcholine (PC) lipid bilayers. We demonstrate its incorporation inside the hydrophobic lipid core and the effect on the pac...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1039/C5NR04719F

Authors


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Institution:
University of Oxford
Department:
Oxford, MPLS, Physics
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Physics, Condensed Matter Physics
Role:
Author
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Funding agency for:
Contera, S
Publisher:
Royal Society of Chemistry Publisher's website
Journal:
Nanoscale Journal website
Volume:
7
Pages:
17102-17108
Publication date:
2015-01-01
DOI:
EISSN:
2040-3372
ISSN:
2040-3364
URN:
uuid:640d8b84-0ee5-4f53-b148-5760877facaf
Source identifiers:
571176
Local pid:
pubs:571176

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