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A common space approach to comparative neuroscience

Abstract:
Comparative neuroscience is entering the era of big data. New high-throughput methods and data-sharing initiatives have resulted in the availability of large, digital data sets containing many types of data from ever more species. Here, we present a framework for exploiting the new possibilities offered. The multimodality of the data allows vertical translations, which are comparisons of different aspects of brain organization within a single species and across scales. Horizontal translations compare particular aspects of brain organization across species, often by building abstract feature spaces. Combining vertical and horizontal translations allows for more sophisticated comparisons, including relating principles of brain organization across species by contrasting horizontal translations, and for making formal predictions of unobtainable data based on observed results in a model species.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1146/annurev-neuro-100220-025942

Authors


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Institution:
University of Oxford
Division:
MSD
Sub department:
Clinical Neurosciences
Role:
Author


Publisher:
Annual Reviews
Journal:
Annual Review of Neuroscience More from this journal
Volume:
44
Publication date:
2021-02-03
Acceptance date:
2020-11-23
DOI:
EISSN:
1545-4126
ISSN:
0147-006X


Language:
English
Pubs id:
1162443
Local pid:
pubs:1162443
Deposit date:
2021-02-25

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