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A novel form of the membrane protein CD147 that contains an extra Ig-like domain and interacts homophilically

Abstract:

Background: CD147 is a broadly distributed integral membrane glycoprotein with two g-like domains implicated in a wide range of functions. It is associated at the cell surface with the monocarboxylate transporters MCT1 and 4 but interactions of the extracellular region have not been characterised. Results: We report the characterisation of a form of CD147 with an additional membrane-distal Ig-like domain. In contrast to the two domain form, this three domain form of CD147 interacts homophilic...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1471-2091-4-17

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
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Medical Research Council More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
BMC Biochemistry Journal website
Volume:
4
Article number:
17
Publication date:
2003-11-01
DOI:
ISSN:
1471-2091
Language:
English
Subjects:
UUID:
uuid:63bb024c-c775-4383-9393-e54c2701ac68
Local pid:
ora:2245
Deposit date:
2008-08-12

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