- Abstract:
-
Over the last decade, the Tec family of nonreceptor tyrosine kinases (Btk, Tec, Bmx, Itk, and Rlk) have been shown to play a key role in inflammation and bone destruction. Bruton's tyrosine kinase (Btk) has been the most widely studied due to the critical role of this kinase in B-cell development and recent evidence showing that blocking Btk signaling is effective in ameliorating lymphoma progression and experimental arthritis. This review will examine the role of TFK in myeloid cell function...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.3109/08830185.2012.670334
-
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- Journal:
- International reviews of immunology
- Volume:
- 31
- Issue:
- 2
- Pages:
- 87-103
- Publication date:
- 2012-04-05
- DOI:
- EISSN:
-
1563-5244
- ISSN:
-
0883-0185
- URN:
-
uuid:63b99cde-10e7-4fda-bed2-203a13a28b89
- Source identifiers:
-
322931
- Local pid:
- pubs:322931
- Language:
- English
- Keywords:
- Copyright date:
- 2012
Journal article
Tec family kinases in inflammation and disease.
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