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Corticospinal transmission to leg motoneurones in human subjects with deficient glycinergic inhibition.

Abstract:

Normal coordinated movement requires that the activity of antagonistic motoneurones may be depressed at appropriate times during the movement. Both glycinergic and GABAergic inhibitory mechanisms participate in this control. Patients with the major form of hyperekplexia (hereditary startle disease) have impaired inhibition of spinal motoneurones from local glycinergic interneurones and represent an ideal opportunity for studying the role of glycinergic inhibition in the control of antagonisti...

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Publisher copy:
10.1113/jphysiol.22.024091

Authors


Journal:
Journal of physiology More from this journal
Volume:
544
Issue:
Pt 2
Pages:
631-640
Publication date:
2002-10-01
DOI:
EISSN:
1469-7793
ISSN:
0022-3751
Language:
English
Keywords:
Pubs id:
pubs:122425
UUID:
uuid:63b817e1-a838-4399-94ca-8aaaf3646780
Local pid:
pubs:122425
Source identifiers:
122425
Deposit date:
2013-02-20

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