The structure and ligand interactions of CD2: implications for T-cell function.

Journal article

Considerable progress has recently been made in understanding the structure and ligand interactions of the T-cell antigen CD2, to the extent that CD2 is now a useful paradigm for considering the structural basis of cell-cell recognition. Here, Simon Davis and Anton van der Merwe review the new data and consider their implications for T-cell function in the context of CD2-knockout experiments.

Authors: Davis, S; van der Merwe, P

• Publication status: Published
• Journal: Immunology today
• Volume: 17
• Issue: 4
• Pages: 177-187
• Publication date: 1996-04-01
• DOI: 10.1016/0167-5699(96)80617-7
• ISSN: 0167-5699
• Language: English
• Keywords: Antigens, CD58; Binding Sites; Antigens, CD; Animals; Ligands; Antigens, CD2; T-Lymphocytes; Humans