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Efficacy markers in depression

Abstract:

Current antidepressant agents are similar in efficacy to the original drugs discovered in the 1950s. The development of new treatments for depression is, however, limited by the absence of validated human biomarker models to predict efficacy, clinical profile and dosing. Such models need to meet key criteria for biomarkers including sensitivity, specificity and relevance to depression. Here we review studies exploring whether early changes in emotional processing with antidepressant drug admi...

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Publisher copy:
10.1177/0269881110367722

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Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
Journal:
Journal of Psychopharmacology More from this journal
Volume:
25
Issue:
9
Pages:
1148-1158
Publication date:
2011-09-01
DOI:
EISSN:
1461-7285
ISSN:
0269-8811
Language:
English
Keywords:
Pubs id:
pubs:193005
UUID:
uuid:633bbb8d-a18a-479b-ae1d-fa22fdaa47d1
Local pid:
pubs:193005
Source identifiers:
193005
Deposit date:
2012-12-19

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