Journal article
MOMP from Campylobacter jejuni is a trimer of 18-stranded β-barrel monomers with a Ca(2+) ion bound at the constriction zone.
- Abstract:
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The Gram-negative organism Campylobacter jejuni is the major cause of food poisoning. Unlike Escherichia coli, which has two major porins, OmpC and OmpF, C. jejuni has one, termed major outer membrane protein (MOMP) through which nutrients and antibiotics transit. We report the 2.1-Å crystal structure of C. jejuni MOMP expressed in E. coli and a lower resolution but otherwise identical structure purified directly from C. jejuni. The 2.1-Å resolution structure of recombinant MOMP showed that a...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 1.7MB)
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- Publisher copy:
- 10.1016/j.jmb.2016.09.021
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Authors
Funding
European Federation of Pharmaceutical Industries and Associations
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Journal of Molecular Biology Journal website
- Volume:
- 428
- Issue:
- 22
- Pages:
- 4528-4543
- Publication date:
- 2016-09-01
- Acceptance date:
- 2016-09-26
- DOI:
- EISSN:
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1089-8638
- ISSN:
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0022-2836
- Source identifiers:
-
699010
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:699010
- UUID:
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uuid:63102083-d209-47a1-a275-a04edeea4a3f
- Local pid:
- pubs:699010
- Deposit date:
- 2017-07-13
Terms of use
- Copyright holder:
- Naismith et al
- Copyright date:
- 2016
- Notes:
- © 2016 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
- Licence:
- CC Attribution (CC BY)
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