Journal article
Nanoscale mapping of newly-synthesised phospholipid molecules in a biological cell using tip-enhanced Raman spectroscopy
- Abstract:
-
Nanoscale chemical mapping of newly-synthesised phospholipid molecules inside a mammalian cell is demonstrated using tip-enhanced Raman spectroscopy (TERS) for the first time using mouse pre-adipocyte cells as a model system. Newly-synthesised membrane phospholipid distribution within a pre-adipocyte cell is mapped with <20 nm spatial resolution, overcoming the diffraction limit of confocal Raman spectroscopy via plasmonic enhancement of Raman signals at a TERS tip-apex.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
UK Department for Business, Energy and Industrial Strategy
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Bibliographic Details
- Publisher:
- Royal Society of Chemistry Publisher's website
- Journal:
- Chemical Communications Journal website
- Volume:
- 53
- Pages:
- 2451-2454
- Publication date:
- 2017-02-01
- Acceptance date:
- 2017-01-30
- DOI:
- EISSN:
-
1364-548X
- ISSN:
-
1359-7345
Item Description
- Pubs id:
-
pubs:811772
- UUID:
-
uuid:62fb90c3-4b00-43fc-846d-a50eade06d7f
- Local pid:
- pubs:811772
- Source identifiers:
-
811772
- Deposit date:
- 2017-12-19
Terms of use
- Copyright holder:
- Royal Society of Chemistry
- Copyright date:
- 2017
- Notes:
- ©The Royal Society of Chemistry 2017. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence
- Licence:
- CC Attribution (CC BY)
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