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Journal article

Polymeric cups for cavitation mediated delivery of oncolytic vaccinia virus

Abstract:

Oncolytic viruses (OV) could become the most powerful and selective cancer therapies. However, the limited transport of OV into and throughout tumors following intravenous injection means their clinical administration is often restricted to direct intratumoral dosing. Application of physical stimuli, such as focussed ultrasound, offers a means of achieving enhanced mass transport. In particular, shockwaves and microstreaming resulting from the instigation of an ultrasound-induced event known ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/mt.2016.139

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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
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Name:
Engineering and Physical Sciences Research Council
Grant:
EP/F011547/1
EP/L024012/1
More from this funder
Name:
Research Councils UK
Grant:
Digital Economy Programme grant number EP/G036861/1
Publisher:
Nature Publishing Group
Journal:
Molecular Therapy More from this journal
Publication date:
2016-07-04
Acceptance date:
2016-06-21
DOI:
EISSN:
1525-0024
ISSN:
1525-0016
Keywords:
Pubs id:
pubs:633551
UUID:
uuid:625ecd56-2f88-4bbd-921a-430b2d8da095
Local pid:
pubs:633551
Source identifiers:
633551
Deposit date:
2016-07-13

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