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Parallel evolution leading to impaired biofilm formation in invasive Salmonella strains

Abstract:

Pathogenic Salmonella strains that cause gastroenteritis are able to colonize and replicate within the intestines of multiple host species. In general, these strains have retained an ability to form the rdar morphotype, a resistant biofilm physiology hypothesized to be important for Salmonella transmission. In contrast, Salmonella strains that are host-adapted or even host-restricted like Salmonella enterica serovar Typhi, tend to cause systemic infections and have lost the ability to form th...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1371/journal.pgen.1008233

Authors


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Role:
Author
ORCID:
0000-0003-2568-6005
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0001-7780-2173
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Role:
Author
ORCID:
0000-0003-1133-8093
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Role:
Author
ORCID:
0000-0001-8401-0860
Publisher:
Public Library of Science
Journal:
PLoS Genetics More from this journal
Volume:
15
Issue:
6
Article number:
e1008233
Publication date:
2019-06-24
Acceptance date:
2019-06-07
DOI:
EISSN:
1553-7404
ISSN:
1553-7390
Pmid:
31233504
Language:
English
Keywords:
Pubs id:
pubs:1023089
UUID:
uuid:6239a0bf-9b21-4e79-bbe0-4cee8dbec3fe
Local pid:
pubs:1023089
Source identifiers:
1023089
Deposit date:
2019-07-03

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