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Early effects of hormone replacement therapy on bone.

Abstract:

Estrogen replacement is currently the preferred therapy for postmenopausal osteoporosis, although its mechanism of action remains poorly understood. Its primary action on bone is generally considered to be antiresorptive, but there is evidence in animals to suggest a stimulatory effect on bone formation. We have now attempted to detect a similar effect in humans by administering hormone replacement therapy (estradiol valerate 2 mg/day and dydrogesterone 5 mg/day given in a continuous, combine...

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
Bone More from this journal
Volume:
24
Issue:
3
Pages:
245-248
Publication date:
1999-03-01
DOI:
EISSN:
1873-2763
ISSN:
8756-3282

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