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Evaluation of the genomic diversity of viruses infecting bacteria, archaea and eukaryotes using a common bioinformatic platform: Steps towards a unified taxonomy

Abstract:

Genome Relationship Applied to Virus Taxonomy (GRAViTy) is a genetics-based tool that computes sequence relatedness between viruses. Composite generalized Jaccard (CGJ) distances combine measures of homology between encoded viral genes and similarities in genome organizational features (gene orders and orientations). This scoring framework effectively recapitulates the current, largely morphology and phenotypic-based, family-level classification of eukaryotic viruses. Eukaryotic virus familie...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1099/jgv.0.001110

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
NDM Experimental Medicine
Adriaenssens, EM More by this author
Lavigne, R More by this author
Kropinski, AM More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
NDM Experimental Medicine
Royal University of Leuven More from this funder
Publisher:
Microbiology Society Publisher's website
Journal:
Journal of General Virology Journal website
Volume:
99
Issue:
9
Pages:
1331-1343
Publication date:
2018-07-17
Acceptance date:
2018-06-13
DOI:
EISSN:
1465-2099
ISSN:
0022-1317
Pubs id:
pubs:891118
URN:
uri:622ebbfa-2388-4c31-8126-26225f46a4d3
UUID:
uuid:622ebbfa-2388-4c31-8126-26225f46a4d3
Local pid:
pubs:891118

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