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The impact of SNP density on fine-scale patterns of linkage disequilibrium.

Abstract:

Linkage disequilibrium (LD) is a measure of the degree of association between alleles in a population. The detection of disease-causing variants by association with neighbouring single nucleotide polymorphisms (SNPs) depends on the existence of strong LD between them. Previous studies have indicated that the extent of LD is highly variable in different chromosome regions and different populations, demonstrating the importance of genome-wide accurate measurement of LD at high resolution throug...

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Publication status:
Published

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Publisher copy:
10.1093/hmg/ddh060

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Journal:
Human molecular genetics More from this journal
Volume:
13
Issue:
6
Pages:
577-588
Publication date:
2004-03-01
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
Language:
English
Keywords:
Pubs id:
pubs:32599
UUID:
uuid:6229ddde-d32f-48e0-811b-071d52cbf70b
Local pid:
pubs:32599
Source identifiers:
32599
Deposit date:
2012-12-19

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