Journal article
Benchmarking CRISPR-BP34 for point-of-care melioidosis detection in low-income and middle-income countries: a molecular diagnostics study
- Abstract:
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Background: Melioidosis is a neglected but often fatal tropical disease. The disease has broad clinical manifestations, which makes diagnosis challenging and time consuming. To improve diagnosis, we aimed to evaluate the performance of the CRISPR-Cas12a system (CRISPR-BP34) to detect Burkholderia pseudomallei DNA across clinical specimens from patients suspected to have melioidosis.
Methods: We conducted a prospective, ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 541.2KB, Terms of use)
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- Publisher copy:
- 10.1016/s2666-5247(23)00378-6
Authors
- Publisher:
- Elsevier
- Journal:
- Lancet Microbe More from this journal
- Volume:
- 5
- Issue:
- 4
- Pages:
- E379-E389
- Publication date:
- 2024-03-13
- Acceptance date:
- 2024-03-01
- DOI:
- EISSN:
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2666-5247
- Language:
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English
- Pubs id:
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1875344
- Local pid:
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pubs:1875344
- Deposit date:
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2024-03-26
- ARK identifier:
Terms of use
- Copyright holder:
- Pakdeerat et al.
- Copyright date:
- 2023
- Rights statement:
- © 2023 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
- Licence:
- CC Attribution (CC BY)
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