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Understanding protein mobility in bacteria by tracking single molecules

Abstract:

Protein diffusion is crucial for understanding the formation of protein complexes in vivo and has been the subject of many fluorescence microscopy studies in cells; however, such microscopy efforts are often limited by low sensitivity and resolution. During the past decade, these limitations have been addressed by new super-resolution imaging methods, most of which rely on single-particle tracking and single-molecule detection; these methods are revolutionizing our understanding of molecular ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1016/j.jmb.2018.05.002

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Institution:
University of Oxford
Division:
MPLS Division
Department:
Physics
Oxford college:
St Cross College
Role:
Author
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Biochemistry
Role:
Author
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Biochemistry
Role:
Author
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Funding agency for:
Kapanidis, AN
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Funding agency for:
Kapanidis, AN
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Funding agency for:
Uphoff, S
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Publisher:
Elsevier Publisher's website
Journal:
Journal of molecular biology Journal website
Volume:
430
Issue:
22
Pages:
4443-4455
Publication date:
2018-05-10
Acceptance date:
2018-05-03
DOI:
EISSN:
1089-8638
ISSN:
0022-2836
Pubs id:
pubs:848096
URN:
uri:61f1a730-969b-473c-8762-65e82557eae1
UUID:
uuid:61f1a730-969b-473c-8762-65e82557eae1
Local pid:
pubs:848096

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