Journal article
Phosphine-Catalysed Cyclisation of beta-Hydroxy-alpha,alpha-Difluoroynones
- Abstract:
- 2-Benzylidene-4,4-difluorodihydrofuran-3(2H)-ones were synthesised in 58-86% yield via phosphine-promoted cyclisation of β-hydroxy-α, α-difluoroynones. The benzylidene group was found to be a suitable masked carbonyl group, thereby allowing for the validation of a novel route to 3,3-difluoro-2-hydroxy-γ-lactols. © Georg Thieme Verlag Stuttgart.
- Publication status:
- Published
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Bibliographic Details
- Journal:
- SYNLETT
- Volume:
- 2009
- Issue:
- 11
- Pages:
- 1733-1736
- Publication date:
- 2009-07-01
- DOI:
- EISSN:
-
1437-2096
- ISSN:
-
0936-5214
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- Copyright date:
- 2009
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