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Journal article

Phosphine-Catalysed Cyclisation of beta-Hydroxy-alpha,alpha-Difluoroynones

Abstract:
2-Benzylidene-4,4-difluorodihydrofuran-3(2H)-ones were synthesised in 58-86% yield via phosphine-promoted cyclisation of β-hydroxy-α, α-difluoroynones. The benzylidene group was found to be a suitable masked carbonyl group, thereby allowing for the validation of a novel route to 3,3-difluoro-2-hydroxy-γ-lactols. © Georg Thieme Verlag Stuttgart.
Publication status:
Published

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Publisher copy:
10.1055/s-0029-1217366

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
Journal:
SYNLETT
Volume:
2009
Issue:
11
Pages:
1733-1736
Publication date:
2009-07-01
DOI:
EISSN:
1437-2096
ISSN:
0936-5214
Language:
English
Keywords:
Pubs id:
pubs:41267
UUID:
uuid:61eab7ae-154d-4fff-b311-1a1894c32f41
Local pid:
pubs:41267
Source identifiers:
41267
Deposit date:
2012-12-19

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