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Genotype is an important determinant factor of host susceptibility to periodontitis in the Collaborative Cross and inbred mouse populations.

Abstract:

BACKGROUND: Periodontal infection (Periodontitis) is a chronic inflammatory disease, which results in the breakdown of the supporting tissues of the teeth. Previous epidemiological studies have suggested that resistance to chronic periodontitis is controlled to some extent by genetic factors of the host. The aim of this study was to determine the phenotypic response of inbred and Collaborative Cross (CC) mouse populations to periodontal bacterial challenge, using an experimental periodontitis...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1471-2156-14-68

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Publisher:
BioMed Central
Journal:
BMC Genetics More from this journal
Volume:
14
Issue:
1
Article number:
68
Publication date:
2013-01-01
DOI:
EISSN:
1471-2156
ISSN:
1471-2156
Language:
English
Keywords:
UUID:
uuid:618c02fb-acf7-4b6b-869e-9a269cdff8b9
Local pid:
pubs:419298
Source identifiers:
419298
Deposit date:
2013-11-16

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