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Journal article

Innate lymphoid cells in intestinal inflammation

Abstract:

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine that encompasses Crohn's disease (CD) and ulcerative colitis. The cause of IBD is unknown, but the evidence suggests that an aberrant immune response toward the commensal bacterial flora is responsible for disease in genetically susceptible individuals. Results from animal models of colitis and human studies indicate a role for innate lymphoid cells (ILC) in the pathogenesis of chronic intestinal inflammation...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3389/fimmu.2017.01296

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; NDM Strategic
Oxford college:
Corpus Christi College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; NDM Experimental Medicine
Role:
Author
More from this funder
Name:
National Institute for Health Research
Grant:
Oxford Biomedical Research Centre (BRC) (CVA-C
More from this funder
Name:
Wellcome Trust
Grant:
101734/Z/13/Z/ (AG
More from this funder
Name:
Crohn’s and Colitis UK
Grant:
M/13/3
Publisher:
Frontiers Media
Journal:
Frontiers in Immunology More from this journal
Volume:
8
Issue:
OCT
Article number:
1296
Publication date:
2017-10-13
Acceptance date:
2017-09-27
DOI:
ISSN:
1664-3224
Pmid:
29081776
Language:
English
Keywords:
Pubs id:
pubs:738649
UUID:
uuid:6165a3a4-c809-4984-a3f8-2713e07dfca7
Local pid:
pubs:738649
Source identifiers:
738649
Deposit date:
2017-11-13

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