- Abstract:
-
We demonstrated previously that osteoclasts possess a divalent cation-sensitive "receptor", the Ca2+ receptor. Activation of the Ca2+ receptor by the surrogate cation Ni2+ was shown to elicit an increase in cytosolic [Ca2+] to a peak value followed by an exponential decline. In the present study we examined the influence of surface membrane voltage on the kinetics of Ca2+ receptor inactivation. The K+ ionophore, valinomycin was applied to intercept the declining phase of the cytosolic [Ca2+] ...
Expand abstract - Publisher copy:
- 10.1006/bbrc.1993.1530
-
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- Journal:
- Biochemical and biophysical research communications
- Volume:
- 192
- Issue:
- 3
- Pages:
- 1100-1105
- Publication date:
- 1993-05-05
- DOI:
- EISSN:
-
1090-2104
- ISSN:
-
0006-291X
- URN:
-
uuid:615334ac-c1d0-4622-89bb-a7c3821a0c4a
- Source identifiers:
-
475721
- Local pid:
- pubs:475721
- Copyright date:
- 1993
Journal article
Voltage sensitivity of the osteoclast calcium receptor.
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