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A library of functional recombinant cell-surface and secreted P. falciparum merozoite proteins.

Abstract:

Malaria, an infectious disease caused by parasites of the Plasmodium genus, is one of the world's major public health concerns causing up to a million deaths annually, mostly because of P. falciparum infections. All of the clinical symptoms are associated with the blood stage of the disease, an obligate part of the parasite life cycle, when a form of the parasite called the merozoite recognizes and invades host erythrocytes. During erythrocyte invasion, merozoites are directly exposed to the ...

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Publication status:
Published

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Publisher copy:
10.1074/mcp.o113.028357

Authors


Crosnier, C More by this author
Wanaguru, M More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
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Journal:
Molecular and cellular proteomics : MCP
Volume:
12
Issue:
12
Pages:
3976-3986
Publication date:
2013-12-05
DOI:
EISSN:
1535-9484
ISSN:
1535-9476
URN:
uuid:6147a22d-5f8c-42cf-8a1f-34c6ca60754d
Source identifiers:
445062
Local pid:
pubs:445062

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