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Thesis

Proteases and inhibitors in the interaction between Nicotiana benthamiana and Agrobacterium tumefaciens – systematic analysis and emerging solutions for molecular farming

Abstract:

Nicotiana benthamiana is now an established platform for molecular farming, the production of biopharmaceuticals in plants. Infiltration with Agrobacterium tumefaciens (agroinfiltration) is commonly used to transiently express one or multiple transgenes in N. benthamiana leaves. Agroinfiltrated N. benthamiana is a flexible and scalable recombinant protein (RP) production platform, but is impeded by low RP yields. Plant proteases can degrade RPs and thus...

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Division:
MPLS
Department:
Plant Sciences
Department:
Plant Chemetics Laboratory, Department of Plant Sciences
Role:
Author

Contributors

Role:
Supervisor
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:6146918c-3749-4604-88fa-01d426e4a817
Deposit date:
2018-02-02

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