- Abstract:
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BACKGROUND: Pentoxifylline (PTX) affects many processes that may contribute to the pathogenesis of severe malaria and it has been shown to reduce the duration of coma in children with cerebral malaria. This pilot study was performed to assess pharmacokinetics, safety and efficacy of PTX in African children with cerebral malaria. METHODS: Ten children admitted to the high dependency unit of the Kilifi District Hospital in Kenya with cerebral malaria (Blantyre coma score of 2 or less) received...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 265.7kb)
-
- Publisher copy:
- 10.1186/1475-2875-9-368
-
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- Publisher:
- BioMed Central Ltd. Publisher's website
- Journal:
- Malaria Journal Journal website
- Volume:
- 9
- Issue:
- 1
- Pages:
- Article: 368
- Publication date:
- 2010
- DOI:
- EISSN:
-
1475-2875
- ISSN:
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1475-2875
- URN:
-
uuid:6136b868-0dcd-4a23-b384-67f6d2966a0b
- Source identifiers:
-
185679
- Local pid:
- pubs:185679
- Copyright holder:
- Lell et al.
- Copyright date:
- 2010
- Notes:
- © 2010 Lell et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Journal article
Pentoxifylline as an adjunct therapy in children with cerebral malaria.
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