Risk factors for human infection with avian influenza A H5N1, Vietnam, 2004.

Journal article

To evaluate risk factors for human infection with influenza A subtype H5N1, we performed a matched case-control study in Vietnam. We enrolled 28 case-patients who had laboratory-confirmed H5N1 infection during 2004 and 106 age-, sex-, and location-matched control-respondents. Data were analyzed by matched-pair analysis and multivariate conditional logistic regression. Factors that were independently associated with H5N1 infection were preparing sick or dead poultry for consumption < or =7 days before illness onset (matched odds ratio [OR] 8.99, 95% confidence interval [CI] 0.98-81.99, p = 0.05), having sick or dead poultry in the household < or =7 days before illness onset (matched OR 4.94, 95% CI 1.21-20.20, p = 0.03), and lack of an indoor water source (matched OR 6.46, 95% CI 1.20-34.81, p = 0.03). Factors not significantly associated with infection were raising healthy poultry, preparing healthy poultry for consumption, and exposure to persons with an acute respiratory illness.

Authors: Dinh, P; Long, H; Tien, N; Hien, N; Mai, L

• Journal: Emerging infectious diseases
• Volume: 12
• Issue: 12
• Pages: 1841-1847
• Publication date: 2006-12-01
• DOI: 10.3201/eid1212.060829
• EISSN: 1080-6059
• ISSN: 1080-6040
• Language: English
• Keywords: Child, Preschool; Case-Control Studies; Humans; Influenza, Human; Adult; World Health Organization/Global Outbreak Alert and Response Network Avian Influenza Investigation Team in Vietnam; Animals; Risk Factors; Female; Influenza A Virus, H5N1 Subtype; Male; Poultry Diseases; Vietnam; Child; Zoonoses; Logistic Models; Adolescent; Questionnaires; Infant