- Abstract:
-
The central role of the placenta in the pathogenesis of pre-eclampsia is undisputed. The evidence that maternal syndrome of pre-eclampsia is caused by a maternal systemic inflammatory response (MSIR) is reviewed. The polymorphic nature of the inflammatory network explains the diversity of the varied signs of this condition. A key observation is that an MSIR is also a feature of normal third trimester pregnancy, but less severe than in pre-eclampsia. Hence pre-eclampsia is simply the extreme e...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1053/plac.2002.0930
-
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- Journal:
- Placenta
- Volume:
- 24 Suppl A
- Issue:
- SUPPL. A
- Pages:
- S21-S27
- Publication date:
- 2003-04-05
- DOI:
- EISSN:
-
1532-3102
- ISSN:
-
0143-4004
- URN:
-
uuid:612489cb-98ae-4869-b3d6-cf3b0fa0ddd5
- Source identifiers:
-
248189
- Local pid:
- pubs:248189
- Language:
- English
- Keywords:
- Copyright date:
- 2003
Journal article
Pre-eclampsia, the placenta and the maternal systemic inflammatory response--a review.
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