Journal article icon

Journal article

Safety profile of the viral vectors of attenuated fowlpox strain FP9 and modified vaccinia virus Ankara recombinant for either of 2 preerythrocytic malaria antigens, ME-TRAP or the circumsporozoite protein, in children and adults in Kenya

Abstract:

Background. We are developing a heterologous prime-boost vaccine strategy against malaria. This approach uses sequential immunization with different vectors to deliver a common preerythrocytic malaria antigen. Preliminary evidence of efficacy and safety has been previously documented in studies from an area where malaria is nonendemic. Additional safety data from an area where malaria is endemic are now required before larger-scale studies are undertaken to determine the efficacy of this vacc...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:

Authors


More by this author
Institution:
"Kenya Medical Research Institute, Centre for Geographical Medical Research (Coast), Kilifi, Kenya", "University of Oxford"
Department:
Medical Sciences Division - Clinical Vaccinology and Tropical Medicine,Centre for (CCVTM)
More by this author
Institution:
"Kenya Medical Research Institute, Centre for Geographical Medical Research (Coast), Kilifi, Kenya"
More by this author
Institution:
University of Oxford
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of - Human Genetics,Wellcome Trust Centre for Human Genetics
More by this author
Institution:
"Kenya Medical Research Institute, Centre for Geographical Medical Research (Coast), Kilifi, Kenya"
More by this author
Institution:
"Kenya Medical Research Institute, Centre for Geographical Medical Research (Coast), Kilifi, Kenya"
Expand authors...
More from this funder
Funding agency for:
Philip Bejon
More from this funder
Funding agency for:
Adrian V. S. Hill
More from this funder
Funding agency for:
Kevin Marsh
Publisher:
University of Chicago Press Publisher's website
Journal:
Clinical Infectious Diseases Journal website
Volume:
42
Issue:
8
Pages:
1102-10
Publication date:
2006-04-05
ISSN:
1058-4838
URN:
uuid:610c089b-431b-456c-821b-94df8e183824
Local pid:
ora:995

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP