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Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study

Abstract:

Background Indian Asians, who make up a quarter of the world's population, are at high risk of developing type 2 diabetes. We investigated whether DNA methylation is associated with future type 2 diabetes incidence in Indian Asians and whether differences in methylation patterns between Indian Asians and Europeans are associated with, and could be used to predict, differences in the magnitude of risk of developing type 2 diabetes.

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/S2213-8587(15)00127-8

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author


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Funder identifier:
https://ror.org/0187kwz08
Grant:
NF-SI-0611-10099


Publisher:
Elsevier
Journal:
Lancet Diabetes and Endocrinology More from this journal
Volume:
3
Issue:
7
Pages:
526-534
Publication date:
2015-06-18
Acceptance date:
2015-04-27
DOI:
EISSN:
2213-8595
ISSN:
2213-8587
Pmid:
26095709


Language:
English
Pubs id:
pubs:533569
UUID:
uuid:60d23f1a-1746-412f-8608-3bbd6a5f9a9d
Local pid:
pubs:533569
Source identifiers:
533569
Deposit date:
2019-10-29

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