Journal article icon

Journal article

Antiviral immune responses in Itk-deficient mice.

Abstract:

Mice lacking Itk, a T-cell-specific protein tyrosine kinase, have reduced numbers of T cells and reduced responses to allogeneic major histocompatibility molecules. This study analyzed antiviral immune responses in mice deficient for Itk. Primary cytotoxic T-lymphocyte (CTL) responses were analyzed after infection with lymphocytic choriomeningitis virus (LCMV), vaccinia virus (VV), and vesicular stomatitis virus (VSV). Ex vivo CTL activity was consistently reduced by a factor of two to six fo...

Expand abstract
Publication status:
Published

Actions


Authors


Journal:
Journal of virology
Volume:
71
Issue:
10
Pages:
7253-7257
Publication date:
1997-10-05
EISSN:
1098-5514
ISSN:
0022-538X
URN:
uuid:60b1ff34-40a0-4bc3-ac24-071bd3962383
Source identifiers:
469163
Local pid:
pubs:469163

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP