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Linking GABA and glutamate levels to cognitive skill acquisition during development

Abstract:

Developmental adjustments in the balance of excitation and inhibition are thought to constrain the plasticity of sensory areas of the cortex. It is unknown however, how changes in excitatory or inhibitoryneurochemical expression (glutamate, g-aminobutyric acid (GABA)) contribute to skill acquisition duringdevelopment. Here we used single-voxel proton magnetic resonance spectroscopy (1H-MRS) to reveal howdifferences in cortical glutamate vs. GABA ratios relate to face proficiency and working me...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1002/hbm.22921

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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
Publisher:
Wiley Publisher's website
Journal:
Human Brain Mapping Journal website
Volume:
36
Issue:
11
Pages:
4334-4345
Publication date:
2015-10-23
Acceptance date:
2015-07-16
DOI:
EISSN:
1097-0193
ISSN:
1065-9471
URN:
uuid:60a147b2-f1e3-43b2-82bd-938b03d56bdf
Source identifiers:
575357
Local pid:
pubs:575357

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