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Journal article

Genome cartography through domain annotation.

Abstract:
The evolutionary history of eukaryotic proteins involves rapid sequence divergence, addition and deletion of domains, and fusion and fission of genes. Although the protein repertoires of distantly related species differ greatly, their domain repertoires do not. To account for the great diversity of domain contexts and an unexpected paucity of ortholog conservation, we must categorize the coding regions of completely sequenced genomes into domain families, as well as protein families.

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Authors


Ponting, CP More by this author
Dickens, NJ More by this author
Journal:
Genome biology
Volume:
2
Issue:
7
Pages:
Comment-2006
Publication date:
2001
DOI:
EISSN:
1465-6914
ISSN:
1465-6906
URN:
uuid:60874790-b133-4c60-9987-3ff8b67d6251
Source identifiers:
237993
Local pid:
pubs:237993

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