Journal article
Efficient enantioselective synthesis of tetramic acids and lactams from threonine
- Abstract:
- Regioselective Dieckmann and aldol cyclisations using an N-acyloxazolidine derived from threonine give substituted tetramic acids and pyroglutamates in high yield and enantioselectivity. These are easily deprotected under mild conditions to give products, some of which exhibit antibacterial activity. © 2007 Elsevier Ltd. All rights reserved.
- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.tetlet.2007.08.052
Authors
- Journal:
- TETRAHEDRON LETTERS More from this journal
- Volume:
- 48
- Issue:
- 41
- Pages:
- 7259-7262
- Publication date:
- 2007-10-08
- DOI:
- ISSN:
-
0040-4039
- Language:
-
English
- Pubs id:
-
pubs:40541
- UUID:
-
uuid:607b3406-4258-440e-b313-60da9dc4e620
- Local pid:
-
pubs:40541
- Source identifiers:
-
40541
- Deposit date:
-
2012-12-19
- ARK identifier:
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- Copyright date:
- 2007
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