The pFC plays a key role in flexible, context-specific decision making. One proposal [Machens, C. K., Romo, R., and Brody, C. D. Flexible control of mutual inhibition: A neural model of two-interval discrimination. Science, 307, 1121-1124, 2005] is that prefrontal cells may be dynamically organized into opponent coding circuits, with competitive groups of cells coding opposite behavioral decisions. Here, we show evidence for extensive, temporally evolving opponent organization in the monkey p...Expand abstract
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Target detection by opponent coding in monkey prefrontal cortex.
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