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Factors Associated with Retention in Routine Well-Care Visits Among Children of Adolescent Mothers Living With and Without HIV: A Community-Based Study in the Eastern Cape, South Africa

Abstract:
Objective: To describe well-care visit attendance among children of adolescent mothers living with HIV and HIV-negative adolescent mothers and identify factors associated with optimal retention in the well-care visit schedule up to 18 months. Design, setting, participants: Cross-sectional data were used from a community-based observational cohort study of adolescent mothers (10–19 years; n=481) and their children (≥19 months old; n=502) in the Eastern Cape, South Africa. Outcome: Optimal well-care visit retention up to 18 months was defined as attending visits within 4 weeks of the recommended child age, attending the 18-month visit and missing no more than one scheduled visit. Results: Attendance was highest at the 6-week visit (88.4%; 95% confidence interval (CI) 85.6% to 91.3%) and lowest at the 18-month visit (58.0%, 95% CI 53.6% to 62.3%). About one-third (36.1%; 95% CI 31.8% to 40.3%) of children were retained to 18 months. Retention was highest among children living in rural vs urban areas (adjusted odds ratio (aOR)=2.01, 95% CI 1.32 to 3.06), those born to mothers whose highest education at pregnancy was secondary versus primary school (aOR=2.73, 95% CI 1.60 to 4.65), born via caesarean section vs vaginal birth (aOR=1.65, 95% CI 1.05 to 2.60) and living closer to the clinic (aOR=0.52, 95% CI 0.28 to 0.96 for long vs short distance). There was weak evidence that retention was lower among children of mothers living with HIV (aOR=0.64, 95% CI 0.40 to 1.02) and higher among food-secure children (aOR=2.18, 95% CI 0.96 to 4.96) and those receiving the child support grant (aOR=1.71, 95% CI 0.92 to 3.16). Conclusions: Universal interventions are needed for retention beyond the neonatal period for children of adolescent mothers living with HIV and HIV-negative adolescent mothers. Interventions must address structural barriers, especially for adolescent mothers with primary education and in urban areas. Future research should examine the underlying mechanisms linking mode of delivery with well-care retention.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1136/bmjopen-2025-106412

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Institution:
University of Oxford
Division:
SSD
Department:
Social Policy & Intervention
Sub department:
Social Policy & Intervention
Role:
Author
ORCID:
0000-0001-8828-5685
More by this author
Institution:
University of Oxford
Division:
SSD
Department:
Social Policy & Intervention
Sub department:
Social Policy & Intervention
Role:
Author
ORCID:
0000-0002-3800-3173
More by this author
Institution:
University of Oxford
Division:
SSD
Department:
Social Policy & Intervention
Sub department:
Social Policy & Intervention
Role:
Author
More by this author
Role:
Author
ORCID:
0000-0003-3547-7936
More by this author
Role:
Author
ORCID:
0000-0002-3305-7738


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Funder identifier:
https://ror.org/0472cxd90
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Funder identifier:
https://ror.org/02jx3x895
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Funder identifier:
https://ror.org/02dg0pv02
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Funder identifier:
https://ror.org/006ss0h52
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Funder identifier:
https://ror.org/0281jqk77


Publisher:
BMJ Publishing Group
Journal:
BMJ Open More from this journal
Volume:
15
Issue:
12
Pages:
e106412
Article number:
bmjopen-2025-106412
Publication date:
2025-12-31
Acceptance date:
2025-12-22
DOI:
EISSN:
2044-6055
ISSN:
2044-6055


Language:
English
Keywords:
Pubs id:
2355870
UUID:
uuid_603e2c15-bea5-4844-a210-3c79da27e280
Local pid:
pubs:2355870
Source identifiers:
3643228
Deposit date:
2026-01-08
ARK identifier:
This ORA record was generated from metadata provided by an external service. It has not been edited by the ORA Team.

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