Journal article
Mobile elements drive recombination hotspots in the core genome of Staphylococcus aureus
- Abstract:
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Horizontal gene transfer is an important driver of bacterial evolution, but genetic exchange in the core genome of clonal species, including the major pathogen Staphylococcus aureus, is incompletely understood. Here we reveal widespread homologous recombination in S. aureus at the species level, in contrast to its near-complete absence between closely related strains. We discover a patchwork of hotspots and coldspots at fine scales falling against a backdrop of broad-scale trends in rate vari...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 1.6MB, Terms of use)
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- Publisher copy:
- 10.1038/ncomms4956
Authors
Bibliographic Details
- Publisher:
- Nature Publications
- Journal:
- Nature Communications More from this journal
- Volume:
- 5
- Pages:
- Article 3956
- Publication date:
- 2014-05-23
- Acceptance date:
- 2014-04-24
- DOI:
- ISSN:
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2041-1723
- Pmid:
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24853639
Item Description
- Language:
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English
- Keywords:
-
- Pubs id:
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pubs:465923
- UUID:
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uuid:5ffaac82-0f77-4a5b-9cdd-accd5fbbe370
- Local pid:
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pubs:465923
- Source identifiers:
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465923
- Deposit date:
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2017-08-30
Terms of use
- Copyright holder:
- Macmillan Publishers Limited
- Copyright date:
- 2014
- Notes:
- ©2014 Macmillan Publishers Limited. All rights reserved. This work is licensed under a Creative Commons Attribution 3.0 Unported License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material.
- Licence:
- CC Attribution (CC BY)
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