Journal article icon

Journal article

Mobile elements drive recombination hotspots in the core genome of Staphylococcus aureus

Abstract:

Horizontal gene transfer is an important driver of bacterial evolution, but genetic exchange in the core genome of clonal species, including the major pathogen Staphylococcus aureus, is incompletely understood. Here we reveal widespread homologous recombination in S. aureus at the species level, in contrast to its near-complete absence between closely related strains. We discover a patchwork of hotspots and coldspots at fine scales falling against a backdrop of broad-scale trends in rate vari...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1038/ncomms4956

Authors


More by this author
Institution:
University of Oxford
Oxford college:
St John's College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
Expand authors...
Publisher:
Nature Publications Publisher's website
Journal:
Nature Communications Journal website
Volume:
5
Pages:
Article 3956
Publication date:
2014-05-23
Acceptance date:
2014-04-24
DOI:
ISSN:
2041-1723
Pmid:
24853639
Source identifiers:
465923

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP