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Weekly platinum-based chemotherapy versus 3-weekly platinum-based chemotherapy for newly diagnosed ovarian cancer (ICON8): quality-of-life results of a phase 3, randomised, controlled trial

Abstract:

Background The ICON8 study reported no significant improvement in progression-free survival (a primary endpoint) with weekly chemotherapy compared with standard 3-weekly treatment among patients with epithelial ovarian cancer. All ICON8 patients were eligible to take part in the accompanying health-related quality-of-life study, which measured the effect of treatment on self-reported wellbeing, reported here.

Methods In this open-label, randomi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/S1470-2045(20)30218-7

Authors

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Division:
MSD
Department:
Oncology
Oxford college:
Hertford College
Role:
Author
ORCID:
0000-0001-8783-3491


Publisher:
Elsevier
Journal:
Lancet Oncology More from this journal
Volume:
21
Issue:
7
Pages:
969-977
Publication date:
2020-06-29
Acceptance date:
2020-03-31
DOI:
EISSN:
1474-5488
ISSN:
1470-2045


Language:
English
Keywords:
Pubs id:
1097982
Local pid:
pubs:1097982
Deposit date:
2020-04-01
ARK identifier:

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