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Annexin 1, glucocorticoids, and the neuroendocrine-immune interface.

Abstract:

Annexin 1 (ANXA1) was originally identified as a mediator of the anti-inflammatory actions of glucocorticoids (GCs) in the host defense system. Subsequent work confirmed and extended these findings and also showed that the protein fulfills a wider brief and serves as a signaling intermediate in a number of systems. ANXA1 thus contributes to the regulation of processes as diverse as cell migration, cell growth and differentiation, apoptosis, vesicle fusion, lipid metabolism, and cytokine expre...

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Publication status:
Published

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Publisher copy:
10.1196/annals.1366.002

Authors


Buckingham, JC More by this author
Tierney, T More by this author
Flower, RJ More by this author
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Journal:
Annals of the New York Academy of Sciences
Volume:
1088
Issue:
1
Pages:
396-409
Publication date:
2006-11-05
DOI:
EISSN:
1749-6632
ISSN:
0077-8923
URN:
uuid:5e8fcf40-b61a-4b40-83e4-324fd7d2a81f
Source identifiers:
311955
Local pid:
pubs:311955

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