Discovery and validation of biomarkers to guide clinical management of pneumonia in African children
Background. Pneumonia is the leading cause of death in children globally. Clinical algorithms remain suboptimal for distinguishing between severe pneumonia from other causes of respiratory distress like malaria, and between bacterial pneumonia and pneumonia from others causes such as viruses. Molecular tools could improve diagnosis and management.Methods. We conducted a mass spectrometry-based proteomic study to identify and validate markers of severity in 390 Gambian children with pneumonia ...Expand abstract
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- Peer reviewed
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- Huang et al
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Copyright © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America.
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