Background. Pneumonia is the leading cause of death in children globally. Clinical algorithms remain suboptimal for distinguishing between severe pneumonia from other causes of respiratory distress like malaria, and between bacterial pneumonia and pneumonia from others causes such as viruses. Molecular tools could improve diagnosis and management.Methods. We conducted a mass spectrometry-based proteomic study to identify and validate markers of severity in 390 Gambian children with pneumonia ...Expand abstract
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Copyright © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Discovery and validation of biomarkers to guide clinical management of pneumonia in African children
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