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Journal article

Discovery and validation of biomarkers to guide clinical management of pneumonia in African children

Abstract:

Background. Pneumonia is the leading cause of death in children globally. Clinical algorithms remain suboptimal for distinguishing between severe pneumonia from other causes of respiratory distress like malaria, and between bacterial pneumonia and pneumonia from others causes such as viruses. Molecular tools could improve diagnosis and management.Methods. We conducted a mass spectrometry-based proteomic study to identify and validate markers of severity in 390 Gambian children with pneumonia ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1093/cid/ciu202

Authors


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Medical Research Council More from this funder
Wellcome Trust More from this funder
Bill and Melinda Gates Foundation More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
Clinical Infectious Diseases Journal website
Volume:
58
Issue:
12
Pages:
1707-1715
Publication date:
2014-01-01
DOI:
EISSN:
1537-6591
ISSN:
1058-4838
URN:
uuid:5dd3c172-9a65-4dbe-979b-c4d02e7b7832
Source identifiers:
458612
Local pid:
pubs:458612

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