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Genetic dissection of the Leishmania paraflagellar rod, a unique flagellar cytoskeleton structure.

Abstract:

The paraflagellar rod (PFR) is a unique network of cytoskeletal filaments that lies alongside the axoneme in the flagella of most trypanosomatids. While little is known about how two major Leishmania mexicana PFR protein components, PFR1 and PFR2, assemble into this complex structure, previous analysis of PFR2 null mutants demonstrated that the PFR is essential for proper cell motility. The structural roles of PFR1 and PFR2 are now examined through comparison of PFR2 null mutants with new PFR...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Journal of cell science
Volume:
112 ( Pt 16)
Issue:
16
Pages:
2753-2763
Publication date:
1999-08-05
EISSN:
1477-9137
ISSN:
0021-9533
URN:
uuid:5d5e0067-4afd-4b1e-aeba-5fca7ab6c177
Source identifiers:
24790
Local pid:
pubs:24790

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