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MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival.

Abstract:

BACKGROUND: MicroRNAs are small RNA species that regulate gene expression post-transcriptionally and are aberrantly expressed in many cancers including hematological malignancies. However, the role of microRNAs in the pathogenesis of multiple myeloma (MM) is only poorly understood. We therefore used microarray analysis to elucidate the complete miRNome (miRBase version 13.0) of purified tumor (CD138+) cells from 33 patients with MM, 5 patients with monoclonal gammopathy of undetermined signi...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/1745-6150-6-23

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Institution:
University of Oxford
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Institution:
University of Oxford
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Author
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Institution:
University of Oxford
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Author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine
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Author
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Publisher:
BioMed Central Ltd. Publisher's website
Journal:
Biology direct Journal website
Volume:
6
Issue:
1
Pages:
23
Publication date:
2011-01-01
DOI:
EISSN:
1745-6150
ISSN:
1745-6150
URN:
uuid:5ce727f2-9b2f-4b34-8e8d-923dd27c7854
Source identifiers:
154316
Local pid:
pubs:154316

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