Journal article

Comparison Of iNfliximab and ciclosporin in STeroid Resistant Ulcerative Colitis: pragmatic randomised Trial and economic evaluation (CONSTRUCT)

Abstract:: Background: The efficacy of infliximab and ciclosporin in treating severe ulcerative colitis (UC) is proven, but there has been no comparative evaluation of effectiveness. Objective: To compare the clinical effectiveness and cost-effectiveness of infliximab and ciclosporin in treating steroid-resistant acute severe UC. Method: Between May 2010 and February 2013 we recruited 270 participants from 52 hospitals in England, Scotland and Wales to an open-label parallel-group, pragmatic randomised ...
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Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Williams, J. G., Alam, M. F., Alrubaiy, L., Clement, C., Cohen, D., Grey, M., Hilton, M., Hutchings, H. A., Longo, M., Morgan, J. M., Rapport, F. L., Seagrove, A. C., & Watkins, A. (2016). Comparison Of iNfliximab and ciclosporin in STeroid Resistant Ulcerative Colitis: pragmatic randomised Trial and economic evaluation (CONSTRUCT). Health Technology Assessment, 20(44), 1–320.

MLA Style

Williams, JG, et al. “Comparison Of INfliximab and Ciclosporin in STeroid Resistant Ulcerative Colitis: Pragmatic Randomised Trial and Economic Evaluation (CONSTRUCT).” Health Technology Assessment, vol. 20, no. 44, 2016, pp. 1–320.

Chicago Style

Williams, JG, MF Alam, L Alrubaiy, et al. 2016. “Comparison Of INfliximab and Ciclosporin in STeroid Resistant Ulcerative Colitis: Pragmatic Randomised Trial and Economic Evaluation (CONSTRUCT).” Health Technology Assessment 20 (44): 1–320.
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Files:: Williams_et_al_2016_Comparison_Of_iNfliximab.pdf

(Preview, Version of record, pdf, 8.6MB, Terms of use)

Publisher copy:: 10.3310/hta20440

Authors

+ Williams, JG More by this author

Role:: Author
ORCID:: 0000-0002-7015-9055

+ Alam, MF More by this author

Role:: Author
ORCID:: 0000-0003-2590-851X

+ Alrubaiy, L More by this author

Role:: Author
ORCID:: 0000-0002-6340-8244

+ Clement, C More by this author

Institution:: University of Oxford
Role:: Author
ORCID:: 0000-0002-5555-433X

+ Cohen, D More by this author

Role:: Author
ORCID:: 0000-0003-1968-1988

More authors...

+ Health Technology Assessment Programme More from this funder

Grant:: 06/78/03

Publisher:: NIHR Journals Library
Journal:: Health Technology Assessment More from this journal
Volume:: 20
Issue:: 44
Pages:: 1-320
Publication date:: 2016-06-01
DOI:: 10.3310/hta20440
EISSN:: 2046-4924
ISSN:: 1366-5278

Language:: English
Keywords:: Steroid use

Ciclosporin
Pubs id:: 2283034
Local pid:: pubs:2283034
Source identifiers:: W2200319253
Deposit date:: 2025-08-21
ARK identifier:: ark:/29072/ora_5cd1255196834b0aa49d327d75ae4627

Terms of use

Copyright date:: 2016

Licence:: CC Attribution (CC BY)

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