Characterization of biological processes through automated image analysis.
The systems-level analysis of complex biological processes requires methods that enable the quantification of a broad range of phenotypical alterations, the precise localization of signaling events, and the ability to correlate such signaling events in the context of the spatial organization of the biological specimen. The goal of this review is to illustrate that, when combined with modern imaging platforms and labeling techniques, automated image analysis methods can provide such quantitati...Expand abstract
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