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Journal article : Review

Paleovirology of the DNA viruses of eukaryotes

Abstract:
Paleovirology is the study of ancient viruses and how they have coevolved with their hosts. An increasingly detailed understanding of the diversity, origins, and evolution of the DNA viruses of eukaryotes has been obtained through the lens of paleovirology in recent years. Members of multiple viral families have been found integrated in the genomes of eukaryotes, providing a rich fossil record to study. These elements have extended our knowledge of exogenous viral diversity, host ranges, and the timing of viral evolution, and are revealing the existence of entire new families of eukaryotic integrating dsDNA viruses and transposons. Future work in paleovirology will continue to provide insights into antiviral immunity, viral diversity, and potential applications, and reveal other secrets of the viral world.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.tim.2021.07.004

Authors

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Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Oxford college:
St Hilda's College
Role:
Author


Publisher:
Cell Press
Journal:
Trends in Microbiology More from this journal
Volume:
30
Issue:
3
Pages:
281-292
Publication date:
2021-09-02
Acceptance date:
2021-07-22
DOI:
EISSN:
1878-4380
ISSN:
0966-842X
Pmid:
34483047


Language:
English
Keywords:
Subtype:
Review
Pubs id:
1198234
Local pid:
pubs:1198234
Deposit date:
2021-11-02
ARK identifier:

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