Journal article

Prime-boost immunisation strategies for tuberculosis.

Abstract:: Vaccines against intracellular pathogens such as Mycobacterium tuberculosis need to induce strong cellular immune responses. Heterologous prime-boost immunisation strategies induce higher levels of both CD4+ and CD8+ T cells than homologous boosting with the same vector. Recombinant pox-viruses are particularly good at boosting previously primed T cell responses. Using BCG as the priming immunisation in such a heterologous prime-boost strategy is a practical solution, which allows the beneficial effects of BCG in children to be maintained.

Publication status:: Published

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APA Style

Mcshane, H., & Hill, A. (2005). Prime-boost immunisation strategies for tuberculosis. Microbes and Infection / Institut Pasteur, 7(5-6), 962–967.

MLA Style

Mcshane, H., and A. Hill. “Prime-Boost Immunisation Strategies for Tuberculosis.” Microbes and Infection / Institut Pasteur, vol. 7, nos. 5-6, 2005, pp. 962–67.

Chicago Style

Mcshane, H., and A. Hill. 2005. “Prime-Boost Immunisation Strategies for Tuberculosis.” Microbes and Infection / Institut Pasteur 7 (5-6): 962–67.
Print

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Publisher copy:: 10.1016/j.micinf.2005.03.009

Authors

+ Mcshane, H More by this author

Institution:: University of Oxford
Division:: MSD
Department:: NDM
Sub department:: Jenner Institute
Role:: Author

+ Hill, A More by this author

Role:: Author

Journal:: Microbes and infection / Institut Pasteur More from this journal
Volume:: 7
Issue:: 5-6
Pages:: 962-967
Publication date:: 2005-05-01
DOI:: 10.1016/j.micinf.2005.03.009
EISSN:: 1769-714X
ISSN:: 1286-4579

Language:: English
Keywords:: Immunization Schedule

Humans

Tuberculosis Vaccines

Immunization, Secondary
Pubs id:: pubs:33098
UUID:: uuid:5c1d8292-2af6-4908-8924-abe24cc0ec73
Local pid:: pubs:33098
Source identifiers:: 33098
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_5c1d82922af649088924abe24cc0ec73

Terms of use

Copyright date:: 2005

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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