Journal article
Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution
- Abstract:
-
To identify genetic loci influencing central obesity and fat distribution, we performed a meta-analysis of 16 genome-wide association studies (GWAS, N = 38,580) informative for adult waist circumference (WC) and waist–hip ratio (WHR). We selected 26 SNPs for follow-up, for which the evidence of association with measures of central adiposity (WC and/or WHR) was strong and disproportionate to that for overall adiposity or height. Follow-up studies in a maximum of 70,689 individuals identified t...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Preview, Version of record, pdf, 582.6KB, Terms of use)
-
- Publisher copy:
- 10.1371/journal.pgen.1000508
Authors
Funding
Bibliographic Details
- Publisher:
- Public Library of Science
- Journal:
- PLOS Genetics More from this journal
- Volume:
- 6
- Issue:
- 4
- Article number:
- e1000508
- Publication date:
- 2010-04-01
- DOI:
- ISSN:
-
1553-7390
Item Description
- Pubs id:
-
pubs:54833
- UUID:
-
uuid:5bcf8e38-38f1-4c28-ab08-9a9f824bcbd2
- Local pid:
-
pubs:54833
- Source identifiers:
-
54833
- Deposit date:
-
2012-12-19
Terms of use
- Copyright holder:
- Lindgren et al
- Copyright date:
- 2010
- Notes:
- © 2009 Lindgren et al. This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.
- Licence:
- CC Attribution (CC BY)
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record