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Clinical prediction models incorporating blood test trend for cancer detection: a systematic review, meta-analysis, and critical appraisal

Abstract:

Background: Blood tests used to identify patients at increased risk of undiagnosed cancer are commonly used in isolation, primarily by monitoring whether results fall outside the normal range. Some prediction models incorporate changes over repeated blood tests (or trends) to improve individualized cancer risk identification, as relevant trends may be confined within the normal range.

Objective: Our aim was to critically appraise existing diagnosti...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.2196/70275

Authors

More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
ORCID:
0000-0002-3006-8730
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
College Only
Oxford college:
St Edmund Hall
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author


Publisher:
JMIR Publications
Journal:
JMIR Cancer More from this journal
Volume:
11
Article number:
e70275
Publication date:
2025-06-27
Acceptance date:
2025-05-05
DOI:
EISSN:
2369-1999


Language:
English
Keywords:
Pubs id:
2125021
Local pid:
pubs:2125021
Deposit date:
2025-05-19
ARK identifier:

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